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G. anaphylaxis or urticarial rashes. In such patients, vancomycin should be substituted for penicillin or ampicillin, and combined with gentamicin. 2. Prosthetic Valve Endocarditis The same choice of empiric and definitive antibiotic regimens are recommended for native and prosthetic valve endocarditis. The duration of therapy for prosthetic valve endocarditis is usually 4 to 6 weeks. e. cloxacillin or vancomycin) for a full 6-week period, and that gentamicin be administered for the first 2 weeks.
Investigate and treat parents for genital infection. • Neisseria gonorrhoeae: Ceftriaxone 25 - 50 mg/kg IM as a single dose. Investigate and treat parents for genital infection. • Chlamydial disease in the adult: Oral tetracycline (500 mg 8 hourly) or doxycycline (100 mg 12 hourly) or erythromycin (500 mg 6 hourly) for 7 days, or azithromycin 1 g PO as a single dose. • Gonococcal conjunctivitis in adults: Ceftriaxone 1 g IM as a single dose. , Nocardia or Bacteroides. Treatment consists of mechanical expression of the exudative or granular material from the canaliculi, combined with probing and irrigation of the nasolacrimal system with a penicillin G (100000 U/ml) eyedrop solution.
The half-life of the particular antibiotic is therefore important. There is no data to support more than a single dose. Further doses generally constitute treatment. Note the waste of resources, the in-creased risk of complications and the fact that multiple doses are not associated with increased efficiency. The chosen antibiotics must be active against the most common ex-pected pathogens. g. MRSA outbreak in an individual hospital. g. patients with jaundice or diabetics, or patients who undergo any procedures to insert prosthetic devices, generally warrant antibiotic prophylaxis.