By C.M. Poser
This can be a thoroughly new, totally updated colour atlas-textbook of a number of sclerosis (MS). the 1st of its variety, it bargains unique worth for its illustrations and instructive textual content at the very most modern diagnostic systems for MS. The e-book opens with introductory and heritage info after which covers the pathogenesis of MS related to alteration of the blood-brain barrier. The part on analysis covers IgG and oligoclonal bands within the cerebrospinal fluid; evoked strength stories, together with visible, brainstem auditory, and somatosensory; MRI (magnetic resonance imaging), together with MRI differential analysis regarding ADEM, MDEM, Lyme ailment, and HTLV-I spastic paraparesis; and puppy (positron emission tomography) and SPECT (single photon emission tomography). Concluding sections disguise the gross, microscopic, and electronmicroscopic pathology of MS and the visible procedure in MS, concerning optic and retrobulbar neuritis; fundoscopy, and visible fields. contains bibliographic re ferences and index.
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Additional resources for An Atlas of Multiple Sclerosis
Clin Neurol Neurosurg 1994c;96:103–10 Poser C. Myalgic encephalomyelitis / chronic fatigue syndrome and multiple sclerosis: Differential diagnosis. EOS J Immunol Immunopharmacol 1995a;196:765–71 Poser C. Onset symptoms of multiple sclerosis. J Neurol Neurosurg Psychiatr 1995b;58:253–4 Poser C, Goutières F, Carpentier M-A, et al. Schilder’s myelinoclastic diffuse sclerosis. Pediatrics 1986;77:107–12 Poser C, Hibberd P, Benedikz J, et al. An analysis of the “epidemic” of multiple sclerosis in the Faroe Islands.
A high macrophage density is associated with fibrinogen leakage (yellow). Courtesy of Dr Frederick Gay, Anglia Polytechnic University, Cambridge, UK. , 1997 Figure 18 Increased permeability of the blood–brain barrier in a multiple sclerosis plaque: Sequential scans obtained at 20, 40, 60 and 80 min (counterclockwise) after intravenous injection of gadolinium-68–EDTA. Focal areas of increased tracer uptake are shown both in the right (early scan) and left (tardive scan) hemispheres. Courtesy of Dr Carlo Pozzilli, University of Rome ‘La Sapienza’.
Note the large collection of macrophages. Periodic acid–Schiff (PAS) stain. (Figure 71 shows the CT scan of this patient) ©1998 CRC Press LLC Figure 41 Biopsy specimen of a deep thalamic plaque misdiagnosed as a brain tumor, as seen by Bodian (upper) and phosphotungstic acid– hematoxylin (PTAH; lower) stains. There is an enormous accumulation of macrophages and lymphocytes in the perivascular space and surrounding tissue (X marks the blood vessel) Figure 42 Section of the medulla shows a large lesion that has completely destroyed the left inferior olive.